ea0041ep1086 | Thyroid cancer | ECE2016
Schug Christina
, Wechselberger Alexandra
, Urnauer Sarah
, Schmohl Kathrin A
, Muller Andrea M
, Schwenk Nathalie
, Lauber Kirsten
, Nelson Peter J
, Spitzweg Christine
The tumor-homing property of mesenchymal stem cells (MSC) has led to their use as delivery vehicles for therapeutic genes such as the sodium iodide symporter (NIS), which has convincingly been demonstrated by our recent studies of systemic NIS gene delivery using MSCs as delivery vehicles in both subcutaneous and orthotopic xenograft mouse models. External beam radiation therapy (EBRT) represents a promising tool in the application of engineered MSC (eMSCs)-based gene therapy ...